MRI finding of spinal cord injury with wallerian degeneration
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منابع مشابه
MRI findings in a case of spinal cord Wallerian degeneration following trauma
W degeneration is a well-known entity which represents distal axonal degeneration and myelin disintegration following interruption of any axon from its cellular connection. It was first described by Weller in 1850 and is named after him.1 It is well described entity on imaging in brain but is less well described in spinal cord with only few reports in radiological literature and in post mortem ...
متن کاملMR-pathologic comparisons of wallerian degeneration in spinal cord injury.
PURPOSE To describe the MR manifestations and temporal course of wallerian degeneration that occurs above and below a spinal cord injury, and to compare the MR findings with postmortem histopathology. METHOD Twenty-four postmortem spinal cords from patients with cervical (n = 14), thoracic (n = 6), and lumbar (n = 4) cord injuries were studied with axial T1- and T2-weighted spin-echo MR imagi...
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When neurons within the motor cortex are fatally injured, their axons, many of which project into the spinal cord, undergo wallerian degeneration. Pathological processes occurring downstream of the cortical damage have not been extensively studied. We created a focal forelimb motor cortex injury in rats and found that axons from cell bodies located in the hindlimb motor cortex (spared by the co...
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Wallerian degeneration is a fundamental process of axonal degeneration distal to the injury site. Although axonal degeneration itself is accomplished in a few days, the subsequent process of removing debris, including myelin debris, in the central nervous system takes more time. Since this debris is a potent inhibitor of axonal regeneration, the removal process is critical for functional recove...
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CM101, an antiangiogenic polysaccharide derived from group B streptococcus, was administered by i.v. injection 1 hr post-spinal-cord crush injury in an effort to prevent inflammatory angiogenesis and gliosis (scarring) in a mouse model. We postulated that gliosis would sterically prevent the reestablishment of neuronal connectivity; thus, treatment with CM101 was repeated every other day for fi...
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تاریخ انتشار 2015